Right, an update.
I have changed the settings on JRiver to output at 192kHz irrespective of the source.
I am currently borrowing some ATC actives from an incredibly generous local wammer (separate report to come on that!), so to ensure a level playing field I undertook room measurements again with the current setup.
There is absolutely no doubt in my mind that Dirac is creating some sort of digital distortion right through the frequency range, even when correcting solely on the bass frequencies (under 200Hz).
Switching between Dirac on and off, the filters have the wonderful effect of tightening up the bass and producing a great even response in the low frequencies, but this is clearly at the expense of some sort of digital hardening/distortion/sibilence/dryness, call it what you will, but I'm sure you know what I'm referring to.
Switch Dirac off and everything sounds more natural/vibrant/realistic.
Put simply, Dirac is sucking the life out of the music, which I can only assume is some sort of digital distortion caused by the digital processing.